Is Plant Sterols a Good Strategy to Lower Cholesterol?
نویسندگان
چکیده
منابع مشابه
P02.88. Powdered Red Yeast Rice and Plant Stanols and Sterols to lower cholesterol
Elevated low-density lipoprotein (LDL) cholesterol is a significant risk factor for cardiovascular disease. It is estimated that 42% of females and 34% of males in the USA have elevated total cholesterol. The current mainstay of lipid-lowering therapy utilizes 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor (i.e., statin) medications that lower total cholesterol and LDL chol...
متن کاملDisruption of cholesterol homeostasis by plant sterols.
The ABC transporters ABCG5 and ABCG8 limit absorption and promote excretion of dietary plant sterols. It is not known why plant sterols are so assiduously excluded from the body. Here we show that accumulation of plant sterols in mice lacking ABCG5 and ABCG8 (G5G8-/- mice) profoundly perturbs cholesterol homeostasis in the adrenal gland. The adrenal glands of the G5G8-/- mice were grossly abnor...
متن کاملDietary plant sterols and cholesterol metabolism.
Plant sterols, naturally occurring in foods of plant origin, reduce cholesterol absorption. Experimental studies show plant sterols to be an important part of the serum-cholesterol lowering effect of certain diets and dietary components. Epidemiological data show that individuals with higher intakes of plant sterols from their habitual diets have lower serum-cholesterol levels. To date, the rol...
متن کاملPlant sterols beyond low-density lipoprotein-cholesterol.
Moderate hypercholesterolaemia still remains one of the commonest metabolic disorders in developed societies, largely due to the effect of an inappropriate diet with high intake of saturated and trans fatty acids. This form of hypercholesterolaemia is often accompanied by arterial hypertension which may increase the atherogenicity of even moderately increased concentrations of the LDL fraction....
متن کاملUnesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons.
BACKGROUND Plant sterols, in various forms, have been shown to reduce total and LDL-cholesterol concentrations. Particularly controversial at present is the effect of the degree of hydrogenation of the plant sterols on cholesterol-lowering efficacy and the responsible mechanisms. OBJECTIVE Our goal was to examine the effect of supplementation with unesterified plant sterols and stanols on pla...
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ژورنال
عنوان ژورنال: Journal of Oleo Science
سال: 2019
ISSN: 1345-8957,1347-3352
DOI: 10.5650/jos.ess19116